在住院期间的部脊髓损伤患者深静脉血栓的诺莫格拉姆预测模型
Haifeng Wu1, Jiyuan Ni2, Huixian Sun2
1Department of Orthopedic Surgery, The Third Hospital of Shijiazhuang, Shijiazhuang, People's Republic of China.
World neurosurgery
|July 9, 2025
概括
在创伤性椎脊髓损伤 (SCI) 患者中确定了深静脉血栓 (DVT) 风险因素. 使用这些因素的诺米图模型显示了在住院期间DVT风险的强有力的预测性能.
科学领域:
- 医学研究 医学研究
- 临床诊断 临床诊断 临床诊断
- 血栓形成的研究.
背景情况:
- 深静脉血栓症 (DVT) 是一个严重的并发症,患者有创伤性椎脊髓损伤 (SCI).
- 识别风险因素对于及时预防和在住院期间的管理至关重要.
研究的目的:
- 在患有创伤性宫SCI的患者中确定DVT的独立风险因素.
- 在这个人群中开发和验证对DVT风险的预测性名录模型.
主要方法:
- 分析了580名患有创伤性宫SCI的患者队列.
- 后勤回归确定了独立的风险因素,包括美国脊髓损伤协会等级,联合脑损伤,中性粒细胞与淋巴细胞的比率和D-二次体.
- 使用ROC曲线,校准曲线和决策曲线分析构建并验证了一个名ogram模型.
主要成果:
- 美国脊髓损伤协会的等级,结合的脑损伤,中性粒细胞与淋巴细胞的比率和D-二次体被确定为DVT的独立风险因素.
- 诺米图表表现出良好的预测能力,ROC曲线下的面积在培训队列中为0.808,在验证队列中为0.785.
- 该模型显示出卓越的准确性和临床有效性.
结论:
- 确定的因素是DVT在患有创伤性宫SCI的住院患者的显著预测因素.
- 开发的诺莫格拉姆模型提供了一个强大的工具,用于评估在这个脆弱的患者群体中DVT风险.
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