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在间歇性肺病中使用的咳患者报告的结果措施:系统性审查

Jennifer Mann^1,2,3, Hayley Barnes^4,5, Jeremy Lew⁶

¹Department of Respiratory and Sleep Medicine, Austin Health, Melbourne, Australia jennifer.mann@austin.org.au.

European respiratory review : an official journal of the European Respiratory Society

|July 9, 2025

概括

在间歇性肺病 (ILD) 中咳的患者报告结果测量 (PROM) 有有限的证据支持其测量特性. 需要进一步验证和开发新的PROM,以准确评估咳的严重程度和对ILD患者的影响.

科学领域:

肺部医学肺部医学
临床研究临床研究
健康结果的健康结果.

背景情况:

患者报告的结果测量 (PROM) 对于评估咳严重程度和间歇性肺病 (ILD) 的影响至关重要.
对文献进行系统审查,以确定和评估ILD中咳的PROM.

研究的目的:

系统地审查和评估现有的PROMs在ILD患者咳的心理特征.
确定证据中存在的差距,以支持目前在ILD中咳的PROM.

主要方法:

在2025年1月10日之前,对四个数据库进行系统的文献搜索.
包括英语原始文章的PROMs咳在成年ILD患者,评估心理特征,管理,或可用性.
在35项研究中对21项PROM进行评估.

主要成果:

没有一个单一的PROM证明了对所有七个评估的心理测量属性的充分证据.
四个PROM显示了在异形性肺纤维化 (IPF) 中内容有效性的证据:ATAQ-IPF,CASA-Q,E-RSTM:COPD和L-IPF.
莱斯特咳问卷 (LCQ) 和咳视觉模拟量表 (VAS) 显示了与客观咳监测的高合有效性. 十个PROM显示了可接受的内部一致性.

结论:

目前支持PROMs在ILD中咳的测量特性的证据有限.
需要进一步验证现有的文书.
建议在ILD中开发用于咳的新型疾病特异性PROM.

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