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Updated: Sep 16, 2025

RNA-based Reprogramming of Human Primary Fibroblasts into Induced Pluripotent Stem Cells
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人类T细胞表转录组中的伪尿素重编程:从初级状态到不朽状态

Oleksandra Fanari1, Dylan Bloch1, Yuchen Qiu1

  • 1Department of Bioengineering, Northeastern University, Boston, Massachusetts 02120, USA.

RNA (New York, N.Y.)
|July 9, 2025
PubMed
概括

研究人员比较了初级和永生T细胞中的伪尿素 (ψ) RNA修饰. 大多数 ψ 位点被保存,但Jurkat 细胞中的独特位点与免疫激活和瘤发生有关,而初级细胞显示信号链接.

关键词:
基因组RNA的修改 基因组RNA的改变免疫学 免疫学 免疫学纳米孔直接RNA测序主要的T细胞是T细胞.这是一种伪乌里丁类药物.

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