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Updated: Sep 16, 2025

In Vitro Ubiquitination and Deubiquitination Assays of Nucleosomal Histones
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希斯和PARP1上的氨酸ADPr是以为连接的无处不在的细胞标

Andreas Kolvenbach1, Maria Dilia Palumbieri1, Thomas Colby1

  • 1Max Planck Institute for Biology of Ageing, Cologne, Germany.

Nature chemical biology
|July 9, 2025
PubMed
概括

研究人员发现了一种新的细胞修饰:ADP-ribosyl-ubiquitylation. 这个过程将无处不在与胺ADP-ribosylation联系起来,揭示了对DNA损伤反应和细胞信号通路的新见解.

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