Nghi M Nguyen1,2,3, Pranavi Athota1, Adrian Flores1

  • 1Department of Anesthesiology, University of Nebraska Medical Center (UNMC), Omaha, NE, USA.

PubMed
概括

新生儿暴露于常见的ICU镇静剂米达佐拉姆 (MDZ) 可以导致长期的神经发育问题. 这项研究表明,新生儿慢性使用MDZ会改变身体发育,大脑化学和成年后的行为.

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Long-term potentiation, or LTP, is one of the ways by which synaptic plasticity—changes in the strength of chemical synapses—can occur in the brain. LTP is the process of synaptic strengthening that occurs over time between pre and postsynaptic neuronal connections. The synaptic strengthening of LTP works in opposition to the synaptic weakening of long-term depression (LTD) and together are the main mechanisms that underlie learning and memory.
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