在2018年和2022年注射药物的人中,PrEP护理级联的变化
Hunter C Spencer1, Matthew A Town2,3, LaLaine Sevillano2,3
1Department of General Internal Medicine, Oregon Health and Sciences University, 3181 SW Sam Jackson Park Rd., PortlandPortland, OR, 97239, USA. spencerh@ohsu.edu.
AIDS and behavior
|July 9, 2025
概括
艾滋病毒暴露前预防 (PrEP) 意识在注射毒品 (PWID) 的人群中从2018年到2022年增加. 然而,PrEP的获取和使用率仍然很低,这阻碍了在这个人群中结束艾滋病毒传播的努力.
科学领域:
- 公共卫生 公共卫生
- 预防传染病 预防传染病
- 医疗保健服务研究 医疗服务研究
背景情况:
- 艾滋病毒暴露前预防 (PrEP) 是预防艾滋病毒传播的关键工具.
- 在注射药物使用者 (PWID) 中使用PrEP不足仍然是一个重大的公共卫生挑战,即使在临床上有指示.
研究的目的:
- 评估2018年至2022年期间在俄勒冈州波特兰的PWID中对PrEP意识,获取和利用的变化.
- 在2022年确定与PWID人口中PrEP意识相关的因素.
主要方法:
- 分析了2018年和2022年国家艾滋病毒行为监测 (NHBS) 调查周期的数据.
- 2018年至2022年间使用千平方测试对准备剂的认识,获取和使用情况进行比较.
- 普森回归分析,以评估2022年PrEP意识的变化,并确定相关因素.
主要成果:
- 预备预防措施的认识从2018年的17%显著增加到2022年的33% (aPR=1.24).
- 在2018年至2022年期间,没有观察到PrEP获取或使用的显著变化.
- 在2022年,与白人非西班牙裔PWID相比,西班牙裔个人和先前接受过药物治疗的人群中,PrEP意识更高.
结论:
- 虽然PrEP意识在PWID中有所改善,但这并没有转化为更多的获取或使用.
- 目前在PWID中使用PrEP的水平不足以实现国家艾滋病毒预防目标,例如在结束艾滋病毒流行病倡议中概述的目标.
- 需要有针对性的干预措施来改善注射药物使用者对PrEP的获取和使用.
相关概念视频
Healthcare Associated Infections II: Preventive Measures
2.8K
Essential infection prevention measures are based on the knowledge of the infection chain, the modes of transmission in healthcare settings, and the use of the best practices in all healthcare settings. Compulsory public reporting of healthcare-associated infection rates is needed to allow individuals and the community to make informed choices regarding selecting a healthcare facility.
The best practices for preventing healthcare-associated infections include hand hygiene, patient risk...
The best practices for preventing healthcare-associated infections include hand hygiene, patient risk...
2.8K
Factors Affecting Drug Response: Overview
2.4K
When it comes to infants and young children, they are typically administered smaller doses of medication in comparison to adults. This is primarily because their organ functions still need to fully develop, meaning their bodies are not as efficient at metabolizing or eliminating drugs. Additionally, their blood-brain barrier is more permeable than in adults. As a result, high concentrations of drugs can easily penetrate the central nervous system (CNS), potentially leading to neurological...
2.4K
Standard Precaution
2.2K
Standard precautions are the minimum infection control safeguards used while caring for all patients, irrespective of their disease condition. They help prevent the spread of common infectious microorganisms to healthcare workers, patients, and visitors in all healthcare settings.
Hand hygiene is the most crucial means to prevent the transmission of disease. Employers are legally required to provide their workers with personal protective equipment (PPE) to minimize exposure or contact with...
Hand hygiene is the most crucial means to prevent the transmission of disease. Employers are legally required to provide their workers with personal protective equipment (PPE) to minimize exposure or contact with...
2.2K
Issues And Trends In Healthcare Delivery System
5.9K
The issues and trends in healthcare delivery are constantly changing. The COVID-19 pandemic is one recent issue that wreaked havoc on healthcare systems, causing a shortage of healthcare workers, high demand for medicines and supplies, and increased medical expenditure due to a lack of insurance. Other issues include rising healthcare costs and care fragmentation.
Cost Containment
Payment for healthcare services has historically promoted adoption of costly and often unnecessary or inefficient...
Cost Containment
Payment for healthcare services has historically promoted adoption of costly and often unnecessary or inefficient...
5.9K
Drug Delivery: Parenteral Route
864
The parenteral route is a critical method of drug administration. It delivers compounds directly into the systemic circulation and bypasses the gastrointestinal tract. This approach is particularly advantageous for drugs that exhibit poor absorption or instability when administered orally.
There are three primary parenteral routes: intravenous (IV), intramuscular (IM), and subcutaneous (SC). The IV route introduces the drug directly into the bloodstream, ensuring immediate action. The IM route...
There are three primary parenteral routes: intravenous (IV), intramuscular (IM), and subcutaneous (SC). The IV route introduces the drug directly into the bloodstream, ensuring immediate action. The IM route...
864
Drug Delivery: Miscellaneous Routes
471
Drug delivery methods like oral inhalation, nasal sprays, transdermal patches, eye drops, intravitreal injection, and rectal administration provide localized effects with reduced toxicity.
Oral inhalation and nasal sprays swiftly transfer drugs across the respiratory epithelium's mucosal layer. Inhaled glucocorticoids and bronchodilators directly target lung conditions such as asthma, while fluticasone nasal spray mitigates allergic rhinitis.
Transdermal patches transport drugs...
Oral inhalation and nasal sprays swiftly transfer drugs across the respiratory epithelium's mucosal layer. Inhaled glucocorticoids and bronchodilators directly target lung conditions such as asthma, while fluticasone nasal spray mitigates allergic rhinitis.
Transdermal patches transport drugs...
471


