在儿童早期患有赫施普朗格病的患者中排便功能障碍的特征
Shiwen Pan1, Wei Li2, Chengpeng Shi3,4
1Department of Anesthesia and Operation, Children's Hospital of Nanjing Medical University, Nanjing, 210008, China.
BMC gastroenterology
|July 9, 2025
概括
排便功能障碍在患有赫施普朗格病 (HD) 的儿童中很常见,随着更长的角质细分而恶化. 这些问题持续到成年期,影响社会福祉.
科学领域:
- 儿科手术 儿科手术
- 胃肠病学 胃肠病学
- 发展生物学 发展生物学
背景情况:
- 希尔施普朗格病 (HD) 中的排便功能障碍可以持续到成年期,导致社会问题.
- 儿童早期的HD便功能障碍的特征基于角质细分长度尚未得到充分确立.
研究的目的:
- 为了识别和描述早期儿童HD患者的排便功能障碍特征.
- 为了将功能障碍的严重程度与角质细分长度相关联.
主要方法:
- 一个问卷 (肠功能评分 (BFS)) 评估了204名患有HD的儿童和156名对照儿童的排便状态.
- 根据角质段的长度,HD患者被分为直筒状 (RSHD),下降/横向 (DTHD) 和上升/横向 (AIHD) 组.
- 在HD组和对照组中比较了BFS结果.
主要成果:
- 排便功能障碍率为27.7% (RSHD),71.8% (DTHD) 和100% (AIHD),明显高于对照组 (P < 0.05).
- 功能障碍的严重程度和特定问题 (无法延迟/报告排便冲动,污染,事故,社会问题) 随着角质段的长度 (P < 0.05) 增加.
- 便秘不是一个普遍的问题,功能障碍与RSHD/DTHD组的年龄无关.
结论:
- 排便功能障碍在童年早期所有HD类型中普遍存在,随着更长的角质细分而恶化.
- 关键的功能障碍特征包括便冲动受损,污垢,事故和社会问题,所有这些都因段子长度而加剧.
- 功能障碍的严重程度不会随着年龄的增长而改善,在儿童早期的HD.
相关概念视频
Assessment of the Rectum and Anus
412
Evaluating the rectum and anus plays a crucial role in conducting a thorough physical examination of the gastrointestinal system. Although it may be uncomfortable and often embarrassing for the patient, it holds immense diagnostic value, particularly in detecting gastrointestinal diseases and abnormalities. This guide will explain how to perform this assessment using inspection and palpation methods.
Rectal Inspection
Begin by inspecting the perianal and anal areas for color, texture, rashes,...
Rectal Inspection
Begin by inspecting the perianal and anal areas for color, texture, rashes,...
412
Feces Formation and Defecation
1.6K
After spending 3 to 10 hours in the large intestine, chyme loses a lot of water and becomes feces, the final product of digestion. Feces consist of undigested dietary fiber such as cellulose, mucus, sloughed-off epithelial cells, and microbes. The descending and sigmoid colon stores feces and uses haustral contractions to dry it out but retains enough water to give it a semi-solid texture.
The mass peristalsis then pushes the feces into the rectum, which stretches the rectal walls to activate...
The mass peristalsis then pushes the feces into the rectum, which stretches the rectal walls to activate...
1.6K
Irritable Bowel Syndrome II: Clinical Features and Diagnostic Evaluation
253
Irritable Bowel Syndrome II: Clinical Features and Diagnostic Evaluation
Irritable Bowel Syndrome (IBS) is classified into subtypes based on the predominant bowel habits as determined by the Bristol Stool Form Scale (BSFS). The subtypes are:
Irritable Bowel Syndrome (IBS) is classified into subtypes based on the predominant bowel habits as determined by the Bristol Stool Form Scale (BSFS). The subtypes are:
253
Psychosexual Stages of Personality: Anal
1.9K
Sigmund Freud's theory of psychosexual development describes the anal stage as occurring between 18 months and three years of age. During this period, children derive pleasure from controlling and releasing their bowel movements. However, they quickly learn that societal expectations impose restrictions on when and where this can happen. This stage marks a critical point where children begin to develop a sense of control and mastery over their bodily functions, as well as their broader...
1.9K
Gastrointestinal Motility Disorders
609
Gastrointestinal or GI motility disorders are characterized by irregular gastrointestinal tract movements, disrupting food transit from the mouth to the anus. They are caused by damage or dysfunction in gut muscles or nerves. These disorders can cause symptoms such as severe constipation, diarrhea, abdominal pain, and swallowing difficulties. Disorders can affect any segment of the GI tract and range widely in severity, from common conditions like GERD to life-threatening conditions like...
609
Chronic Bowel Disorders: Introduction
541
Chronic bowel diseases are a group of long-term conditions affecting the digestive tract, characterized by inflammation and damage to the gut lining. These conditions primarily include irritable bowel syndrome and inflammatory bowel disease.
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...
Irritable Bowel Syndrome (IBS) is a common disorder affecting the gastrointestinal tract. The distinctive feature is recurrent abdominal pain associated with altered bowel movements, manifesting as constipation, diarrhea, or fluctuating between both. The...
541


