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Updated: Sep 16, 2025

Shunt Surgery, Right Heart Catheterization, and Vascular Morphometry in a Rat Model for Flow-induced Pulmonary Arterial Hypertension
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聚乙烯通过抑制内皮细胞到介质细胞的过渡来减轻实验性肺动脉高血压

Jie Wang1,2, Yu Zhang1,2, Junjun Liu1,2

  • 1Department of Geriatric Medicine and Laboratory of Gerontology and Anti-Aging Research, Qilu Hospital of Shandong University, Jinan, Shandong, China.

Frontiers in pharmacology
|July 10, 2025
PubMed
概括

聚乙烯 (PTE) 通过减少血管重塑,有效地治疗大鼠的肺动脉高血压 (PAH). 这种天然化合物通过HMGA下调来抑制内皮细胞到介质细胞的过渡 (EndMT),提供作为补充PAH治疗的潜力.

关键词:
斯奈尔 (Snail) 是一个动物.内皮细胞到介质细胞的过渡.高流动性小组 AT-hook 的高流动性小组甲是一种甲.肺动脉高血压 肺动脉高血压一个扭曲的扭曲.

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