中性粒细胞 - 淋巴细胞比率和剖腹产后疼痛之间的关系在宫下关节阻塞下进行的剖腹产患者中:一项前性观察性研究
Roopa Sachidananda1, Alisha Malipatil1, Vikas Joshi1
1Department of Anaesthesia, Karnataka Institute of Medical Sciences, Hubli, Karnataka, India.
Journal of anaesthesiology, clinical pharmacology
|July 10, 2025
概括
手术后的中性粒细胞淋巴细胞比率 (NLR) 与剖腹产后的视觉模拟尺度 (VAS) 疼痛评分有显著的相关性. 这表明NLR可以作为一个客观的生物标志物来评估产科患者的急性疼痛.
科学领域:
- 产科和妇科 产科和妇科
- 疼痛管理 疼痛管理
- 血液学 血液学 血液学
背景情况:
- 剖腹产是一个常见的产科手术.
- 评估术后疼痛对于患者的康复至关重要.
- 手术创伤会引起急性相应反应,改变白细胞数量.
研究的目的:
- 为了研究术后中性粒细胞淋巴细胞比率 (NLR) 和疼痛强度之间的关系.
- 评估NLR作为术后疼痛的客观指标.
- 为了将NLR与视觉模拟尺度 (VAS) 疼痛分数相关联.
主要方法:
- 对120名接受选择性剖腹产的妇女进行前性观察性研究.
- 使用视觉模拟尺度 (VAS) 评估疼痛.
- 中性细胞淋巴细胞比率 (NLR) 由手术前和手术后的血液样本计算. 斯皮尔曼的等级相关性用于分析.
主要成果:
- 手术后的NLR明显高于手术前的NLR.
- 在手术后12,24小时和48小时,VAS得分和NLR之间观察到显著的正相关性.
- 在接受重复剖腹产的患者中,在24小时内注意到更高的狄克洛菲纳克需求.
结论:
- 手术后的中性粒细胞淋巴细胞比率 (NLR) 与视觉模拟尺度 (VAS) 疼痛得分有显著的相关性.
- 在剖腹产后的客观疼痛评估中,NLR可以被用作可靠的代孕标志物.
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