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改变生命的基本8调解了肠道微生物群的饮食指数和睡眠障碍之间的相关性
Juanjuan Fang1, Zhenhua Wang1, Jiangshui Yu1
1The Second Affiliated Hospital of Fujian Medical University, Quanzhou, China.
Frontiers in nutrition
|July 10, 2025
概括
肠道微生物群 (DI-GM) 饮食指数的更高得分与更少的睡眠障碍有关. 修改生命的基本8 (mLE8) 健康评分在此方面发挥着作用.
科学领域:
- 营养科学 营养科学
- 睡眠医学 睡眠医学
- 微生物组研究 微生物组研究
背景情况:
- 肠道微生物群在睡眠障碍中的作用尚未完全理解.
- 需要进行研究来澄清肠道微生物群 (DI-GM) 的饮食指数与睡眠病理生理学之间的关系.
研究的目的:
- 调查DI-GM与睡眠障碍的患病率之间的联系.
- 探索修改生命的基本8 (mLE8) 评分在这种关系中的调解作用.
主要方法:
- 利用了2007-2018年国家健康和营养检查调查 (NHANES) 的数据.
- 采用多变量逻辑回归和受限立方线 (RCS) 模型.
- 进行了调解分析,以评估mLE8及其组件的作用.
主要成果:
- 较高的DI-GM和DI-GM有益得分与睡眠障碍的发病率降低相关 (ORs < 1).
- 观察到剂量-反应关系,较高的得分表明睡眠障碍风险较低.
- mLE8得分显著介导了DI-GM和睡眠障碍之间的关联,约占影响的14.46%.
结论:
- 坚持适合肠道微生物群的饮食,如DI-GM分数较高所示,与睡眠障碍的发病率较低有关.
- mLE8得分在饮食-睡眠障碍关系中起着重要的调解作用,强调了整体健康行为的重要性.
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