TCMKD:从古老的智慧到现代的见解 - - 一个全面的平台,用于传统中医知识的发现
Wenke Xiao1, Mengqing Zhang2, Danni Zhao2
1State Key Laboratory of Southwestern Chinese Medicine Resources, Innovative Institute of Chinese Medicine and Pharmacy, Chengdu University of Traditional Chinese Medicine, Chengdu, 611137, China.
Journal of pharmaceutical analysis
|July 10, 2025
概括
我们开发了传统中医知识发现 (TCMKD) 平台,以标准化和整合TCM数据. TCMKD提供分析工具和问答系统,以探索TCM的药理基础及其与现代医学的整合.
科学领域:
- 综合医学是一个整体的医学.
- 计算生物学是一种计算生物学.
- 药理学 药理学是指药理学的学科.
背景情况:
- 传统中医 (TCM) 拥有广泛的历史医学知识.
- 数据标准化,完整性和准确性的挑战阻碍了TCM研究,因为资源分散.
- 整合中医与现代医学需要强大的数据管理和分析工具.
研究的目的:
- 为传统中医知识发现 (TCMKD) 开发一个全面的平台.
- 应对数据挑战,促进TCM与现代科学见解的整合.
- 为探索TCM治疗的分子基础提供分析工具.
主要方法:
- 整合和手动校对七个关键的TCM数据类型:综合症,配方,中国专利药物 (CPD),中国药用材料 (CMM),成分,目标和疾病.
- 实施分析方法,包括TCM数据挖掘,丰富分析和网络本地化/分离.
- 集成快速问答系统和TCM文本注释工具,以实现高效的数据查询和文本挖掘.
主要成果:
- 在TCMKD平台 (https://cbcb.cdutcm.edu.cn/TCMKD/) 成功整合和标准化各种TCM数据.
- 在TCMKD中的分析工具阐明了TCM和现代医学之间的分子级联系.
- 该平台增强了TCM知识的发现,并促进了高效的数据访问和分析.
结论:
- TCMKD作为一个关键的存储库,以了解TCM的药理学基础.
- 该平台的分析工具和方法可以适应其他传统医疗系统的研究.
- 中医医科促进了传统中医与当代科学研究的融合.
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