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在中国患者的胃肠镜检查过程中,新的西普罗与普罗波相比:一个元分析

Xiaoyan Liang¹, Qing Feng², Guozhen Li³

¹School of Public Health, Xinjiang Medical University, Urumqi, China.

Frontiers in medicine

|July 10, 2025

概括

在接受胃肠镜检查的中国患者中,西普罗提供了与普罗波相似的手术结果. 这种新型麻醉剂还显示了副作用的风险降低,包括注射疼痛和呼吸抑制.

科学领域:

麻醉学麻醉学
胃肠病学胃肠病学
药理学药理学是指药理学的学科.

背景情况:

胃肠道内镜干预是常见的程序.
普罗波是标准麻醉剂.
齐普罗是一种新的麻醉剂,在中国批准用于胃肠内镜.

研究的目的:

在接受胃肠镜检查的中国患者中,系统地比较西普罗与普罗波的疗效和安全性.

主要方法:

对12项涉及2055名中国患者的研究进行了元分析 (1073名接受了西普罗,982名接受了普罗波).
比较程序结果 (诱导时间,清醒时间,持续时间,恢复时间) 和不良药物事件.
使用RevMan软件进行统计分析 (RR和WMD具有95%的CI).

主要成果:

与propofol相比,西普罗福在诱导时间,手术持续时间或恢复时间上没有显著差异.
西普罗与明显缩短的清醒时间 (P=0.03) 和恢复时间 (P=0.007) 相关.
与普罗相比,西普罗显著降低了注射疼痛,呼吸抑制,低血压和昏昏欲睡的风险.

结论:

齐普罗似乎是中国患者胃肠镜检查中普罗的安全有效替代品.
西普罗与更糟糕的程序结果或增加不良事件无关.
由于分析的局限性,建议进行进一步的研究来证实这些发现.

关键词:

中国参与者的中国参与者.药物不良事件是药物不良事件.酸 (Ciprofol) 是一种酸.结肠镜检查结肠镜检查胃镜检查 (gastroscopy) 是一种检查.普罗波福尔 (Propofol) 是一种

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