在线嵌入针治疗肥胖症中应用多甘油酸/多 (乳酸-同甘油酸):新策略和挑战
Jinkun Wang1,2, Kangdi Cao2, Zhaoyi Chen1
1Department of Acupuncture and Moxibustion, Beijing Hospital of Traditional Chinese Medicine, Capital Medical University, Beijing Key Laboratory of Acupuncture Neuromodulation, Beijing, People's Republic of China.
概括
使用多糖酸 (PGA) 或多 (乳糖-同-糖酸) (PLGA) 线程的线程嵌入针 (TEA) 有效地降低体重并改善肥胖患者的代谢健康. 本综述探讨了其肥胖管理的机制,应用和挑战.
科学领域:
- 综合医学是一个整体的医学.
- 代谢健康 代谢健康
- 针研究 针研究
背景情况:
- 肥胖是一个主要的全球健康问题,与许多慢性疾病有关.
- 线嵌入针 (TEA),利用可吸收的PGA/PLGA线在针点中,正在成为一种新的肥胖管理策略.
- 现有的文献缺乏对TEA用于治疗肥胖症的全面审查.
研究的目的:
- 审查PGA/PLGA线程在肥胖治疗中嵌入针的临床应用,潜在机制,新兴策略和挑战.
- 巩固当前关于TEA在控制肥胖的有效性和潜力的知识.
- 确定未来研究和临床标准化的领域.
主要方法:
- 在PubMed,Web of Science和Embase数据库中进行了系统的文献搜索.
- 关键词包括"针嵌入线程"",针嵌入针"",肥胖"和"肥胖",数据收集到2024年.
- 该审查综合了临床研究中关于TEA对肥胖个体的影响的研究结果.
主要成果:
- 临床研究表明,TEA可显著降低肥胖患者的体重,腰围和食欲.
- TEA在调节全身炎症和增强脂肪细胞代谢能力方面表现出潜力.
- 该疗法影响肠道微生物群,神经内分泌通路和下丘脑功能,通过勒素受体激活影响食欲控制和能量稳定.
结论:
- 线嵌入针通过影响多个生理途径,显示出对肥胖管理的显著治疗潜力.
- 关于标准化针点选择,嵌入深度和治疗频率的挑战仍然存在.
- 需要进一步的研究和标准化,以建立TEA作为一种实用且广泛采用的临床方法来治疗肥胖症.
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