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Updated: Sep 16, 2025

Combining Mitotic Cell Synchronization and High Resolution Confocal Microscopy to Study the Role of Multifunctional Cell Cycle Proteins During Mitosis
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Combining Mitotic Cell Synchronization and High Resolution Confocal Microscopy to Study the Role of Multifunctional Cell Cycle Proteins During Mitosis

Published on: December 5, 2017

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通过CDK驱动的TRAIP酸化对于线粒体复制体分解和MiDAS是必不可少的

Divyasree Poovathumkadavil1, Alicja Reynolds-Winczura1, Aggeliki Skagia1

  • 1Department of Cancer and Genomic Sciences, Birmingham Centre for Genome Biology, University of Birmingham, Birmingham, B15 2TT, United Kingdom.

Nucleic acids research
|July 10, 2025
PubMed
概括

TRAIP从DNA中卸载了复制机制 (复制体). 循环素依赖激酶 (CDK) 酸化在线粒分裂中激活 TRAIP,但不是在 S 阶段,防止不受控制的复杂体移除并保持基因组稳定性.

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