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Updated: Sep 16, 2025

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白色-棕色切换控制了Candida auris的表型可塑性和毒性

Trinh Phan-Canh1, Sabrina Jenull2, Tamires Bitencourt3

  • 1Max Perutz Labs Vienna, Vienna Biocenter Campus (VBC), Dr.-Bohr-Gasse 9, 1030 Vienna, Austria; Medical University of Vienna, Center for Medical Biochemistry, Dr.-Bohr-Gasse 9/2, 1030 Vienna, Austria; Medical University of Vienna, Department of Dermatology, Währinger Gürtel 18-20, 1090 Vienna, Austria.

Cell reports
|July 10, 2025
PubMed
概括

黄菌表现出白细胞和棕细胞状态之间的可逆切换,影响其毒性和抗真菌耐药性. 这种由环境因素驱动的可塑性提供了潜在的治疗点.

关键词:
CP: 微生物学 微生物学它们是Candida auris.白色-棕色的切换开关抗真菌易感性 抗真菌易感性表观遗传学是指表观遗传学.健身 健身 健身 健身 健身 健身免疫逃避 免疫逃避在物种内部的变化变化.形态发生 (morphogenesis) 是一种形态的产生.现型切换的切换是表型切换.转录调节器是指转录调节器.

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