与正常型患者相比,唐氏综合征患者的牙缺陷和皮之间的关联
Paula Esther Alves Cruz1, Juliane Rolim de Lavôr1, Samylla Glória de Araújo Costa1
1Universidade de Pernambuco - UPE, School of Dentistry, Department of Pediatric Dentistry, Recife, PE, Brazil.
Brazilian oral research
|July 10, 2025
概括
与同龄人相比,患有唐氏综合征 (DS) 的儿童的牙缺陷率较高,但牙损伤率较低. 这项研究突显了DS儿童口腔健康的显著差异.
科学领域:
- 儿科牙科 儿科牙科
- 遗传学 是一个遗传学.
- 口腔健康研究研究 口腔健康研究
背景情况:
- 唐氏综合征 (DS) 与各种健康状况有关,包括潜在的口腔健康挑战.
- 牙面膜发育缺陷 (DDE) 和牙腐烂是儿童常见的口腔健康问题.
- 了解DS,DDE和之间的相互作用对于有针对性的预防策略至关重要.
研究的目的:
- 调查DS和没有DS的儿童中DDE和牙的流行情况.
- 探索DS,DDE和牙之间的联系.
- 为了比较患有DS和没有DS的儿童之间的口腔健康结果.
主要方法:
- 一项横截面的探索性研究,涉及71名6至11岁的儿童 (10名患有DS,61名没有).
- 使用标准化表格评估dmft/DMFT (牙虫) 和修改后的DDE.
- 统计分析包括皮尔森的千平方,曼-惠特尼测试,以及几率比率的计算.
主要成果:
- 患有DS的儿童患有明显更高的DDE (p < 0.001) 和较低的牙损伤 (p = 0.007) 的流行率.
- 患有DS的个体患有DDE的可能性是9.8倍 (p = 0.018).
- 划定不透明度是观察到的最常见的DDE类型.
结论:
- 患有唐氏综合征的儿童表现出明显的口腔健康状况,其特点是增加了DDE和减少了脏病的流行率.
- 这些发现表明,在患有DS的儿童中,可能与DDE相关的潜在的防作用.
- 需要进一步的研究来阐明这些观察到的差异背后的机制.
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