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Updated: Sep 16, 2025

Iterative Optimization of DNA Duplexes for Crystallization of SeqA-DNA Complexes
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Iterative Optimization of DNA Duplexes for Crystallization of SeqA-DNA Complexes

Published on: November 1, 2012

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对于7-Deazaadenine/Thymine的银结合二分法:更喜欢沃森-克里克配对而不是DNA中的同基相互作用

Carmen López-Chamorro1, Antonio Pérez-Romero1, Alicia Domínguez-Martín1

  • 1Departamento de Química Inorgánica, Universidad de Granada, Avda. Fuentenueva s/n, 18071 Granada, Spain.

Inorganic chemistry
|July 10, 2025
PubMed
概括

银离子优先与修改后的DNA结合,有利于X-T序列中的标准配对. 研究人员在金属化DNA中发现了新的X-Ag+-X同基对,进步了金属DNA纳米结构设计.

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Author Spotlight: Characterizing DNA G-Quadruplex by Bis-3-Chloropiperidine Based Chemical Mapping05:32

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Sequence-specific and Selective Recognition of Double-stranded RNAs over Single-stranded RNAs by Chemically Modified Peptide Nucleic Acids09:04

Sequence-specific and Selective Recognition of Double-stranded RNAs over Single-stranded RNAs by Chemically Modified Peptide Nucleic Acids

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For successful DNA replication, the unwinding of double-stranded DNA must be accompanied by stabilization and protection of the separated single strands of the DNA. This crucial task is performed by single-strand DNA-binding (SSB) proteins. They bind to the DNA in a sequence-independent manner, which means that the nitrogenous bases of the DNA need not be present in a specific order for binding of SSB proteins to it. The binding of SSB proteins straightens single-stranded DNA (ssDNA) and makes...
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