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Updated: Sep 16, 2025

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在神经母细胞瘤中TERT促进子突变的临床意义

Natasha Persaud1, Gunes Gundem2, Brian H Kushner1

  • 1Department of Pediatrics, Memorial Sloan Kettering Cancer Center, New York, NY.

JCO precision oncology
|July 10, 2025
PubMed
概括

通过TERT促进子突变 (TERT-PM) 和TERT重组 (TERT-RA) 维持端粒与高危神经母细胞瘤有关. 通常与MYCN放大同时发生的TERT-PM可能表明超高风险的患者群体.

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