在因高级疾病死亡后的悲伤中使用迷幻药:一项广泛的审查
Daniel Rosenbaum1,2, Celina Carter1, Brandon A Cirella1
1UHN Centre for Mental Health - Psychedelic Psychotherapy Research Group, University Health Network, Toronto, ON, Canada.
Omega
|July 10, 2025
概括
迷幻药辅助疗法显示出对悲伤的潜力,但证据有限. 需要更多的研究来指导临床使用在晚期疾病后的丧亲.
科学领域:
- 精神病学是一个精神病学.
- 心理学 心理学 心理学
- 药理学 药理学是指药理学的学科.
背景情况:
- 迷幻药辅助心理治疗显示出与死亡相关的痛苦的前景.
- 关于迷幻药对悲伤的益处的理解有限.
- 晚期疾病和终身护理背景是关键的兴趣领域.
研究的目的:
- 为了对因晚期疾病死亡后的悲伤而使用迷幻药的范围进行审查.
- 探索现有的文献和识别知识差距.
- 综合当前对悲伤中的迷幻干预措施的理解.
主要方法:
- 根据阿斯基和奥马利的框架进行范围审查.
- 遵守PRISMA-ScR报告指南.
- 搜索七个数据库 (2023年4月和12月) 没有限制.
主要成果:
- 从4614份选记录中,包括了18份报告.
- 七项实证研究调查了迷幻药对悲伤的影响.
- 报告的总体上是积极的结果 (减少悲伤严重程度),尽管有限的高质量证据,但很少出现不良事件.
结论:
- 目前缺乏关于在悲伤中使用迷幻药的临床建议的强有力的证据基础.
- 研究人员应该清楚地定位他们的工作,并整合悲伤研究理论.
- 建议在未来的研究中与悲伤治疗师和理论家进行合作.
相关概念视频
01:21Kubler Ross's Stages of Dying
364
Elisabeth Kübler-Ross significantly advanced psychology's understanding of the process of dying with her influential book, On Death and Dying (1969). She focused on studying terminally ill individuals and outlined five stages commonly experienced when coping with death: denial, anger, bargaining, depression, and acceptance.
In denial, individuals reject the reality of their condition, often thinking, "This isn't true; I feel fine," as a way to protect themselves from...
In denial, individuals reject the reality of their condition, often thinking, "This isn't true; I feel fine," as a way to protect themselves from...
364
01:17Bonanno's Theory of Grieving
174
Grieving is a complex psychological and emotional process that varies significantly among individuals. George Bonanno's research on bereavement identified four distinct patterns of grieving, offering a nuanced understanding of how people cope with significant loss, such as the death of a spouse, over extended periods. These patterns — resilience, recovery, chronic dysfunction, and delayed grief — highlight the diversity in emotional responses and adaptive mechanisms.
Resilience
Resilience
174
01:22CNS Stimulants: Psychedelic Agents
253
Hallucinogens, also known as psychedelic drugs, are a class of substances known for their ability to alter perception, cognition, and emotions. Despite their profound effects on the mind, these drugs are non-addictive, setting them apart from many other abused substances. The mechanism of action of these drugs lies in their impact on the 5-HT2A receptor in the brain. Upon activation, this receptor couples to Gq-type G proteins, triggering a cascade that releases intracellular calcium. This...
253
01:27Hallucinogens and Psychedelics
290
Hallucinogens are psychoactive substances that profoundly alter perceptual experiences, generating unreal visual and sensory images. Often referred to as psychedelic drugs — a term derived from the Greek words "psyche" (mind) and "delos" (revealing) — these substances include marijuana and lysergic acid diethylamide (LSD), among others. These drugs vary in intensity and effects.
Marijuana, derived from the dried leaves and flowers of the hemp plant, contains...
Marijuana, derived from the dried leaves and flowers of the hemp plant, contains...
290
01:30Psychosurgery
116
Psychosurgery, the surgical alteration or permanent removal of brain tissue to alleviate severe psychological conditions, stands as one of the most radical and controversial treatments in the history of mental health care. Its development and application have evolved significantly, marked by dramatic shifts in scientific understanding and ethical perspectives.
Historical Development of Psychosurgery
In the 1930s, Portuguese neurologist Antonio Egas Moniz introduced a surgical procedure designed...
Historical Development of Psychosurgery
In the 1930s, Portuguese neurologist Antonio Egas Moniz introduced a surgical procedure designed...
116
01:26Psychosis: Goals of Pharmacotherapy
213
Antipsychotic drugs are a crucial treatment method for acute and chronic psychoses, bipolar illness, and behavioral disorders. The selection of these drugs depends on several factors, including the state of the disease, clinical judgment, possible drug interactions, and the patient's sensitivity to adverse effects. In immediate scenarios, such as delirium and dementia, short-term treatment with low doses of high-potency typical or atypical agents can effectively manage symptom exacerbation.
213