设计用于纸张凝结诊断的彩色乳和红细胞的保留
Anuragmani Tripathi1, Simon Corrie1, Gil Garnier1
1Bioresource Processing Research Institute of Australia (BioPRIA), Department of Chemical and Biological Engineering, Monash University, Clayton, Victoria 3800, Australia.
Journal of colloid and interface science
|July 10, 2025
概括
用于诊断的纸张过依赖于孔径大小,但颗粒大小本身并不能决定保留效率. 粒子弹性和形状显著影响红细胞的过能力,而不是珠子.
科学领域:
- 生物材料工程 生物材料工程
- 表面科学是一门学科.
- 分析化学 分析化学
背景情况:
- 选择合适的纸质基板对于高灵敏度的纸质聚合试验至关重要.
- 分析剂诱导的聚合物与生物合物/颗粒的有效分离取决于纸的孔径大小和过机制.
- 了解过和界面机制是确定最佳纸质材料的关键.
研究的目的:
- 为了测试尺寸排除是诊断纸质材料中生物合体/颗粒过的主要机制的假设.
- 开发一种可重复的方法来确定纸质基板的有效孔隙切断尺寸.
- 为了研究颗粒性质对纸张过过程中的保留效率的影响.
主要方法:
- 开发了一种可复制的方法来测量使用乳颗粒 (0.5-30微米) 的纸张有效孔隙切断尺寸.
- 在受控条件下通过纸过悬浮物后,通过图像分析量化颗粒的保留.
- 与DLVO相互作用能量计算相关联的实验保留,并将红细胞保留与聚乙烯珠子进行比较.
主要成果:
- 诊断纸的有效孔隙切断尺寸被确定为20微米.
- 在测试的论文中,尺寸排除不是较小的合体 (0.5微米) 的主要保留机制.
- 聚乙烯珠子的保留效率与颗粒大小线性增加,较大的颗粒显示和;由于弹性和形状,红细胞的保留效率低于同等珠子.
结论:
- 有效的孔隙切断尺寸是诊断纸张选择的关键参数,在本研究中发现是20微米.
- 诊断纸的过机制很复杂,尺寸排除不是唯一的主导因素,特别是对于较小的颗粒.
- 像弹性和形状这样的粒子特性显著影响保留,需要考虑超出简单的尺寸排除,以优化基于纸张的测试.
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