额头QRS-T角度作为败血症死亡率的早期预测因素
Rukiye Çaprak1, Furkan Çağrı Oğuzlar1, Hamit Hakan Armağan1
1Medical Faculty of Suleyman Demirel University, Emergency Medicine Department Isparta, Türkiye.
The American journal of emergency medicine
|July 10, 2025
概括
额头QRS-T角度,心脏再极化的一种测量方法,预测了败血症患者的30天死亡率. 这种非侵入性的心电图发现有助于在急诊室早期评估风险.
科学领域:
- 心脏病学 心脏病学
- 临界护理医学 临界护理医学
- 医学诊断 医学诊断 医学诊断
背景情况:
- 败血症具有显著的死亡风险,特别是在老年人和慢性病患者中.
- 在败血症中准确和及时的风险分层仍然是一个临床挑战.
- 额头QRS-T角度 (F-QRS-T) 反映了心室再极化异质性,在心血管和炎症疾病中具有预后价值.
研究的目的:
- 评价前额QRS-T角度作为30天死亡率的早期预测器,在进入急诊室的败血症患者.
- 为了确定F-QRS-T角度和败血症结果之间的关联.
主要方法:
- 从2022年9月到2024年9月,对456名成人败血症患者 (败血症-3标准) 进行了回顾性队列研究.
- 12导电心电图 (ECG) 在呈现后一小时内进行.
- 收集了有关人口统计,临床因素,实验室结果和30天全因死亡率的数据.
主要成果:
- 与幸存者 (55.2°,p < 0.001) 相比,非幸存者表现出明显更大的F-QRS-T角度 (85.0°).
- 43.5°的F-QRS-T切断角显示出对死亡率的良好歧视 (AUC 0.750).
- 扩大F-QRS-T角度是30天死亡率 (HR=2.805) 的独立预测指标,同时增加CRP,乳酸和MEWS≥2.2.
结论:
- 额头QRS-T角度是一个有价值的,非侵入性和独立的预测器30天死亡率在败血症.
- 它通过标准ECG的常规可用性使其能够在紧急情况下实际集成到现有的风险分层工具中.
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