血液吸收在与癌症相关的并发症中的使用
Vedran Premuzic1,2, Lui G Forni3,4
1Department for Nephrology, Hypertension, Dialysis and Transplantation, University Hospital Center Zagreb, Zagreb, Croatia.
Blood purification
|July 10, 2025
概括
身体外血液净化,包括血吸血,为癌症患者治疗器官衰竭提供了潜力. 这种方法可以准炎症分子,防止毒症和急性损伤 (AKI) 等严重并发症.
科学领域:
- 在瘤学瘤学.
- 腎臟病學 (nephrology) 是一種醫學專業.
- 关键护理医学 关键护理医学
背景情况:
- 转移性癌症患者面临器官衰竭 (AKI,肝衰竭,多器官衰竭) 的风险,由于毒性,败血症和超级炎症 (例如,CAR-T疗法).
- 目前的治疗方法缺乏针对这些危及生命的并发症的特定分子点.
研究的目的:
- 审查体外血液净化技术的潜在使用,特别是血液吸收器,用于管理与癌症有关的并发症.
- 评估血液吸收在特定指示中的有效性及其对器官衰竭的预防作用.
主要方法:
- 对治疗败血症和败血性休克的体外血液净化实验和临床研究的综述.
- 对癌症相关并发症中的hemoadsorber疗效的分析.
主要成果:
- 身体外血液净化技术对癌症患者出现严重并发症有希望.
- 血液吸收可以向和去除炎症分子,类似于其在其他患者群体中的使用.
结论:
- 血液吸收为癌症相关器官功能障碍和衰竭提供了一个可行的治疗选择.
- 随机对照试验证据不足阻碍了更广泛的采用,但其应用应与在其他关键条件下使用保持一致.
相关概念视频
Hemodialysis II: Procedure and Complications
143
DialyzersA hemodialysis (HD) dialyzer is a plastic cartridge containing thousands of parallel hollow fibers, which serve as semipermeable membranes. These fibers are typically made from cellulose-based or other synthetic materials. During HD, blood is pumped into the top of the cartridge and distributed among these fibers. Simultaneously, dialysis fluid, known as dialysate, is introduced into the bottom of the cartridge, bathing the outside of the fibers. Across the semipermeable membrane,...
143
Stem Cell Therapy for Tissue Regeneration
4.2K
Stem cell therapy is a method used in regenerative medicine to repair and restore function to damaged tissues and organs. Stem cells have the potential to proliferate and differentiate into various tissue types, making them ideal candidates for tissue regeneration. For example, hematopoietic stem cell transplants are commonly used in blood cancer treatment to replenish damaged bone marrow and restore healthy blood cells.
Types of Stem Cells used in Stem Cell Therapy
The two main cell...
Types of Stem Cells used in Stem Cell Therapy
The two main cell...
4.2K
Bone Marrow Sampling and Transplants
504
Bone marrow transplant is a potential cure for several diseases, including cancer and specific genetic disorders. Notably, this procedure is applicable for patients suffering from aplastic anemia, certain types of leukemia, severe combined immunodeficiency disease (SCID), Hodgkin's disease, non-Hodgkin's lymphoma, multiple myeloma, thalassemia, sickle-cell disease, and certain cancers.
The transplant begins with high doses of chemotherapy and radiation treatment, which aim to destroy...
The transplant begins with high doses of chemotherapy and radiation treatment, which aim to destroy...
504
Adaptive Mechanisms in Cancer Cells
5.9K
Cancer cells accumulate genetic changes at an abnormally rapid rate due to the defects in the DNA repair mechanisms. From an evolutionary perspective, such genetic instability is advantageous for cancer development. Mutant cell lines accumulate a series of beneficial mutations that contribute to their progression into cancer.
Some of the advantages that cancer cells have on normal cells include - enhanced ability to divide without terminally differentiating, induce new blood vessel formation,...
Some of the advantages that cancer cells have on normal cells include - enhanced ability to divide without terminally differentiating, induce new blood vessel formation,...
5.9K
Hemodialysis I: Introduction
310
Hemodialysis (HD) is a medical treatment that artificially removes waste products, excess fluids, and toxins from the blood when the kidneys are no longer able to perform these functions effectively. In this process, blood is filtered through a semipermeable membrane, allowing for the selective removal of waste while preserving necessary components like blood cells and proteins. Hemodialysis is typically performed in patients with end-stage renal disease (ESRD) or severe kidney...
310
Cancer Therapies
8.0K
Cancer therapies are various modes of treatment, such as surgery, radiation therapy, and chemotherapy that are administered to cancer patients.
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
However, cancer treatments can pose several challenges, as therapies used to kill cancer cells are generally also toxic to normal cells. Moreover, cancer cells mutate rapidly and can develop resistance to chemical agents or radiation therapy. Besides, all types of cancer cells may not respond to the same therapy. Some cancer cells respond to one...
8.0K


