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Updated: Sep 16, 2025

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在人体细胞中协转译蛋白N-myristoylation的机制

Martin Gamerdinger1, Blanca Echeverria2, Alfred M Lentzsch3

  • 1Department of Biology, Molecular Microbiology, University of Konstanz, 78457 Konstanz, Germany.

Molecular cell
|July 10, 2025
PubMed
概括

在N-myristoyltransferases (NMTs) 中,蛋白质被共翻译修改. 这项研究揭示了NMT1在核糖体出口处与METAP1进行交换,形成一个复合体,该复合体在甲氨酸切除后专门针对蛋白质进行N-myristoylation.

关键词:
辅酶A是一种辅酶.这是一种N-乙转移酶.N-终端修改的修改在NAC中,NAC是NAC的代表.在 NMT NMT 中使用.甲氨基胺酶的使用方法这是米里斯蒂克酸.新生的聚相关复合体.核糖体的核糖体是指核糖体中的核糖体.

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