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miR-10a-5p通过准MRTF-A/TGF-β2反循环来抑制心脏纤维化

Chen Liu1, Jinhua Ding1, Xiaojie Chen1

  • 1College of Biotechnology, Tianjin University of Science and Technology, 300457 Tianjin, PR China.

Cellular signalling
|July 10, 2025
PubMed
概括

微RNA-10a-5p (miR-10a-5p) 可以通过抑制肌肉蛋白相关转录因子A (MRTF-A) 来减少心脏纤维化. 这一发现表明miR-10a-5p是心脏病的潜在治疗点.

关键词:
心脏纤维化是什么心脏纤维化细胞信号传递 细胞信号传递肌肉激素相关转录因子-a转化增长因子-β的转化增长因子-β.

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