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Updated: Sep 16, 2025

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PLIN2通过CD36介导的上皮层-介质细胞转换促进结直肠癌的进展

Fan Yang1, Ying Li1, Xue Shang1

  • 1Fudan University, Department of Anesthesiology, Shanghai Cancer Centre and Zhongshan Hospital, Shanghai, China.

Cell death & disease
|July 10, 2025
PubMed
概括

这项研究确定了PLIN2作为结直肠癌 (CRC) 进展的关键调节剂,通过稳定CD36和激活上皮层-介质细胞过渡 (EMT) 来促进瘤生长和转移. 针对PLIN2/CD36途径为CRC提供了一个潜在的治疗策略.

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