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Updated: Sep 16, 2025

Intra-iliac Artery Injection for Efficient and Selective Modeling of Microscopic Bone Metastasis
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分子轴 hnRNPU/circKCNK2/EDC4/IL-11 加剧了RCC的骨解性骨转移

Yiqiu Wang1,2,3, Ding Zhao4, Jiayi Lu1

  • 1Department of Urology, Renji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.

Oncogene
|July 10, 2025
PubMed
概括

一种新型的循环RNA,circKCNK2,在细胞癌骨转移中升级调节,并通过促进IL-11分泌来驱动骨解破坏. 准cirKCNK2为高级RCC提供了一个有前途的治疗策略.

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