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Updated: Sep 16, 2025

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通过USP5介导的PD-L1二维基化调节了黑色素瘤免疫疗法的疗效

Jiaheng Xie1,2, Pengpeng Zhang3, Yuankun Liu4

  • 1Department of Burns and Plastic Surgery, Shenzhen Hospital, Southern Medical University, Shenzhen, Guangdong, People's Republic of China.

Journal of translational medicine
|July 10, 2025
PubMed
概括

USP5稳定PD-L1,促进黑色素瘤的免疫逃生. 抑制USP5通过减少瘤生长和促进T细胞活性来增强抗PD-1疗法,为黑色素瘤治疗提供了一种新的策略.

关键词:
免疫逃脱是为了逃脱免疫.免疫治疗是一种免疫疗法.黑色素瘤是一种黑色素瘤.在PD-L1中.USP5 美国

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