cGAS-STING通路:在癌症中免疫反应的双重调节者和治疗影响

Zhanghao Huang1,2,3, Jun Zhu2,3, You Lang Zhou1,4

  • 1Medical School of Nantong University, Nantong University, Nantong, 226001, China.

概括

循环GMP-AMP合成酶 (cGAS) 刺激干扰素基因 (STING) 途径在癌症免疫中具有双重作用,促进抗瘤反应,同时也使免疫逃避. 了解这种平衡对于开发新的癌症疗法至关重要.

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