脊内麻醉与全身麻醉对老年男性患者进行腹腔镜激进前列腺切除术的影响:一项回顾性研究
Xiaokun Sun1, Nuo Bai2, Kaiping Zhang3
1Anesthesia Operating Room, Qingdao Hiser Hospital Affiliated of Qingdao University (Qingdao Traditional Chinese Medicine Hospital), 266000 Qingdao, Shandong, China.
Archivos espanoles de urologia
|July 11, 2025
概括
与全身麻醉相比,在接受前列腺手术 (LRP) 的老年患者中,脊髓内麻醉减少了恢复时间和应激反应. 这种方法可以通过减少全身压力和大脑影响来改善术后恢复.
科学领域:
- 麻醉学 麻醉学
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 老年医学 老年医学
背景情况:
- 在老年人群中,前列腺癌手术率正在增加.
- 腹腔镜激进前列腺切除术 (LRP) 是这个人口群体中常见的一种手术.
研究的目的:
- 在接受LRP的老年患者中,比较脊内麻醉与全身麻醉的效果.
- 为了评估外科手术后的结果,应激反应和神经学参数.
主要方法:
- 对接受LRP的131名老年患者的回顾性分析.
- 56名接受脊髓内麻醉的患者和70名接受全身麻醉的患者之间的比较.
- 评估外科手术期间的指标,压力标志物 (血清上腺素,北上腺素,皮质醇),P300延迟/幅度以及不良事件发生率.
主要成果:
- 脊内麻醉组显示明显缩短了手术,麻醉开始和恢复时间 (p < 0.05).
- 在手术1,2小时后的脊内治疗组中观察到血清中较低的压力激素水平 (上腺素,上腺素,皮质醇) (p < 0.05).
- 在手术后1到6小时内,脊内治疗组显示P3延迟显著降低,P3振幅增加 (p < 0.001),表明认知影响较小.
结论:
- 脊内麻醉与老年LRP患者的更快恢复和减少外科手术期间的压力有关.
- 这种麻醉技术可以提供神经保护性益处,有助于术后恢复.
- 两组之间在不良反应发生率上没有发现显著差异.
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