让紧急医疗服务参与纳洛的分发,以减少药物过量服用
Bina Ali1, Katharine Atwood1, Ua-Aree Sangpukdee1
1Pacific Institute for Research and Evaluation, Beltsville, MD, USA.
Substance use & misuse
|July 11, 2025
概括
紧急医疗服务 (EMS) 提供者对于在过量现场分发纳洛套件至关重要. 对降低危害的积极态度和成为职业EMS提供者显著增加了纳洛套件的分发.
科学领域:
- 公共卫生 公共卫生
- 紧急医疗 紧急医疗
- 药物成科学 药物成科学
背景情况:
- 增加获得纳洛的机会是减少阿片类药物过量死亡的关键策略.
- 巴尔的摩县卫生部门和EMS实施了纳洛.
- 留在身后的东西.
- 一个程序. 程序.
研究的目的:
- 调查EMS提供商对纳洛套件的分发情况.
- 确定与纳洛套件分发相关的因素.
主要方法:
- 通过在线调查对127家EMS提供商进行横截面研究 (2023年8月至2024年1月).
- 用描述性和后勤回归分析来探索参与者特征,分布率,非分布原因和相关因素.
主要成果:
- 48.8%的EMS提供者报告说在最近一次过量反应时留下了纳洛套件.
- 不分发套装的主要原因包括缺乏时间,套装可用性或患者拒绝/持有.
- 纳洛的分布与积极的减少危害的态度和职业EMS提供者地位有显著的关联.
结论:
- 在减少危害的努力中,EMS提供者至关重要.
- 需要加强培训和支持,以充分整合降低危害的紧急医疗服务,以防止药物过量.
相关概念视频
Drug Delivery: Enteral Route
747
The enteral drug administration involves three primary routes: oral, sublingual, and buccal. Oral ingestion is the most prevalent, safe, economical, and convenient method for drug administration. However, it has certain drawbacks, including limited absorption due to the drug's low water solubility or poor membrane permeability, possible emesis from GI mucosa irritation, destruction of drugs by digestive enzymes or low gastric pH, and irregular absorption along with food or other drugs.
747
Prevention of Further Absorption of Poison
931
In cases of acute poisoning, the primary objective is to prevent further absorption of the toxic substance into the body. Immediate interventions using various decontamination techniques targeting the gastrointestinal (GI) tract can achieve this. Decontamination is crucial to prevent poison from entering the systemic circulation, which involves washing affected areas with water and mild soap and removing contaminated clothing. Once external decontamination is done, attention must be turned to...
931
Cardiopulmonary Resuscitation IV: Pharmacological Management
81
Pharmacologic intervention is crucial in treating cardiac arrest patients during ACLS or Advanced Cardiovascular Life Support. The ACLS algorithms guide the administration of specific drugs based on the patient's cardiac arrest rhythm, which includes pulseless ventricular tachycardia (VT), ventricular fibrillation (VF), asystole, and pulseless electrical activity (PEA).EpinephrineIndication: Epinephrine is the first-line drug for all cardiac arrest rhythms.Mechanism of Action: Epinephrine...
81
Adrenergic Agonists: Therapeutic Uses
984
Adrenergic agonists have diverse therapeutic uses across various medical conditions and emergencies.
Emergency and Intensive Care Unit (ICU) applications: Pressor agents increase blood pressure, heart rate, and contractility in shock and organ failure situations. Dopamine can induce vasodilation and stimulate adrenoceptors. Endogenous catecholamines are effective in treating cardiogenic shock. α2-agonists like clonidine can reverse anesthesia-induced hypertension.
Allergies and...
Emergency and Intensive Care Unit (ICU) applications: Pressor agents increase blood pressure, heart rate, and contractility in shock and organ failure situations. Dopamine can induce vasodilation and stimulate adrenoceptors. Endogenous catecholamines are effective in treating cardiogenic shock. α2-agonists like clonidine can reverse anesthesia-induced hypertension.
Allergies and...
984
Cardiopulmonary Resuscitation III: AED Use
73
Introduction to AEDAn Automated External Defibrillator (AED) is a portable medical device that analyzes the heart's rhythm and, if necessary, delivers an electrical shock to help the heart re-establish an effective rhythm during sudden cardiac arrest (SCA). SCA occurs when the heart suddenly and unexpectedly stops beating, leading to a loss of blood flow to the brain and other vital organs. In such emergencies, time is of the essence, and using an AED, combined with Cardiopulmonary...
73
Opioid Analgesics: Synthetic and Semisynthetic Opioids
438
Synthetic and semisynthetic opioids are pivotal in pain management and tackling opioid addiction. Semisynthetic opioids, including morphinans (morphine derivatives), oxycodone, oxymorphone, hydrocodone, and hydromorphone, have improved pharmacokinetic profiles compared to morphine. Additionally, heroin and 6-MAM (6-Monoacetylmorphine) show better CNS penetration than morphine due to heightened lipid solubility. Hydromorphone, a potent opioid, undergoes hepatic metabolism to form the active...
438


