作为雌激素受体α (ERα) 抑制剂的α-曼戈斯结合氨基酸

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Hanggara Arifian1,2, Rani Maharani3,4, Sandra Megantara1,4

  • 1Department of Pharmaceutical Analysis and Medicinal Chemistry, Faculty of Pharmacy, Universitas Padjadjaran, Jatinangor, West Java, Indonesia.

Journal of biomolecular structure & dynamics
|July 11, 2025
PubMed
概括

这项研究修改了alpha-mangostin以提高乳腺癌治疗的生物可用性. Am1Leu结合物对雌激素受体-α (ERα) 显示出强烈的结合亲和力,与现有疗法相比.

关键词:
氨基酸是氨基酸中的一种.分子对接的分子对接.分子动力学分子动力学作为一个药物学家,他做了一些药物学.α-曼戈斯胺是一种

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