双相酸与无蛋白牛骨矿物质用于鼻地板升高:随机对照试验的系统审查和元分析
Mohammed Alkandari1, Meshari Alkandari1, Rashed Alhallaq2
1Department of Dentistry, Rumaithiya Polyclinic, Kuwait City, KWT.
Cureus
|July 11, 2025
概括
双相酸盐 (BCP) 与去蛋白牛骨矿物质 (DBBM) 相比,在鼻腔底部升高方面表现出优异的结果. BCP促进更多的新骨形成和减少残留的移植材料,以改善牙植入物结果.
科学领域:
- 恢复性牙科 恢复性牙科
- 生物材料科学 生物材料科学
- 口腔和牙面部外科手术
背景情况:
- 脱蛋白牛骨矿物质 (DBBM) 是一种常见的骨头移植,用于鼻增大.
- 双相酸盐 (BCP) 也用于牙科植入物之前的骨增强.
- 这两种材料都适用于鼻增大,但需要直接组织学比较.
研究的目的:
- 系统地审查和元分析BCP与DBBM在鼻底部升高的组织学结果.
- 为了比较BCP和DBBM之间的新骨形成,残留的移植材料和软组织变化.
主要方法:
- 在PubMed,Scopus,Web of Science和CENTRAL的系统文献搜索.
- 包括随机对照试验 (RCT),比较BCP和DBBM的鼻底部升高.
- 用随机效应模型对组织学数据的元分析,包括新的骨形成,残留移植和软组织百分比.
主要成果:
- 分析了10个RCT,包括328名患者和389个植入物.
- 与DBBM相比,BCP表现出明显更高的新骨形成 (MD=3.48).
- 与DBBM相比,BCP产生了较低的残留移植物质 (MD=8.41) 和较高的软组织百分比 (MD=6.01).
结论:
- 与DBBM相比,双相酸盐 (BCP) 在鼻腔底部升高方面提供了增强的组织形态测试结果.
- BCP促进优质的新骨形成和整合,使用较少的残留物质.
- 建议进一步进行高质量的长期RCT,以验证这些发现并标准化协议.
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