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Updated: Sep 16, 2025

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HyenaCircle:一个基于HyenaDNA的预训练的大型语言模型,用于长时间的eccDNA预测

Fuyu Li1, Wenxiang Lu1, Yunfei Bai1

  • 1State Key Laboratory of Digital Medical Engineering, School of Biological Science and Medical Engineering, Southeast University, Nanjing, China.

Frontiers in genetics
|July 11, 2025
PubMed
概括

我们开发了HyenaCircle,这是一个使用大型语言模型和第三代测序的深度学习模型,用于预测长额外染色体圆形DNA (eccDNA). 这种新方法改善了检测这些与疾病相关的DNA结构.

关键词:
深度学习是一种深度学习.这就是我们的eccDNADNA.额外染色体的圆形DNA.大型语言模型长时间eccDNA预测第三代测序系统是第三代测序系统.

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