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女性生殖器切割与不孕不育之间的关系:一个系统的审查和元分析

Narges S Soltani¹, Farahnaz Heshmat², Mohsen Dehghani³

¹Student Research Committee, Mashhad University of Medical Sciences, Mashhad, Iran.

Sultan Qaboos University medical journal

|July 11, 2025

概括

切割女性生殖器官 (FGM) 可能会增加21%的不育率,虽然不是显著的. 消除FGM至关重要,特别是对于年轻女孩来说,以防止潜在的健康后果.

科学领域:

公共卫生公共卫生
生殖健康生殖健康
妇女健康妇女健康

背景情况:

切割女性生殖器官 (FGM) 是一种有害的做法,具有潜在的不良健康后果.
在全球范围内,不孕症是一个重要的生殖健康问题.
女生割礼与不孕不育之间的直接联系需要进一步调查.

研究的目的:

系统地审查和对FGM和不孕症之间的关联进行观测研究进行元分析.
量化女性受过FGM的女性与没有受过FGM的女性不孕的几率.

主要方法:

使用MeSH关键字对在线数据库进行系统的文献搜索,直到2024年1月.
包括分析性横截面研究,使用纽卡斯尔-太华尺度进行质量评估.
使用随机效应模型对95%置信区间 (CI) 的聚合几率比率 (OR) 的元分析.

主要成果:

分析了5项涉及37,146名参与者的研究,3项研究被纳入了元分析.
观察到与女性割礼 (FC) 相关的不育率增加了21% (OR = 1.21,95% CI:0.98-1.50),但这在统计学上并不显著.
在包括的研究之间没有发现显著的异质性 (P = 0.84,I2 = 0.0%).

结论:

在本次审查中,FGM和不孕不育之间没有建立统计学上显著的关系.
观察到的趋势表明,FGM女性的不孕率更高,需要持续关注.
优先考虑消除女性生殖器官切割,特别是在年轻女孩中,对于预防潜在的长期健康问题至关重要.

关键词:

女人的割礼切割女性生殖器官的方法不孕症不孕不育不孕不育不孕不育进行元分析分析.审查审查审查审查

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