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Updated: May 6, 2026

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多路径直流脊柱刺激在SOD1-G93A模型的肌缩侧面硬化症中延长了生存期

Zaghloul Ahmed1,2,3, Sreyashi Samaddar2,4, May Hassieb3

  • 1Department of Physical Therapy, The College of Staten Island, City University of New York, Staten Island, NY, United States.

Frontiers in neurology
|July 11, 2025
PubMed
概括

MultiPath-DCS是一种新型的非侵入性刺激,通过减少神经元过敏和清除有毒蛋白质,在ALS小鼠模型中显著延长了生存期. 这种方法为肌缩性侧面硬化症提供了潜在的疾病修饰疗法.

关键词:
这种疾病被称为ALS (amyotrophic lateral sclerosis).直接电流刺激 (tDCS) 是一种神经保护神经保护脊柱运动神经元幸存率 幸存率 生存率

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Spinal cord injury progresses through two interconnected phases: primary injury and secondary injury.Primary InjuryPrimary injury happens at the moment of trauma and involves immediate mechanical damage to the spinal cord.Compression happens when broken vertebrae, herniated discs, or accumulating blood (such as a hematoma) press directly against the spinal cord, distorting its normal shape and function. In cases of contusion, the cord is bruised by a blunt force (like penetrating injuries or...
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