归因于颗粒物污染的缺血性中风负担的全球模式和趋势:1990年至2021年的变化和2022年至2050年的预测
Erman Wu1,2, Riqing Su1, Tong Tang2
1Neurosurgery Center of the First Affiliated Hospital of Xinjiang Medical University, Ürümqi, Xinjiang, China.
Frontiers in public health
|July 11, 2025
概括
颗粒物污染与全球缺血性中风死亡负担的增加有关. 需要有针对性的战略来打击环境和家庭空气污染,特别是在中低收入地区.
科学领域:
- 环境健康 环境健康
- 流行病学 流行病学
- 心血管疾病研究研究
背景情况:
- 脑卒中是全球主要的死亡原因,空气污染,特别是颗粒物 (PMP),被确定为一个重要的危险因素.
- 缺血性中风比出血性中风更强烈地与空气污染有关.
- 本研究使用最近的数据评估了与PMP相关的缺血性中风的疾病负担,趋势和未来预测.
研究的目的:
- 从1990年到2021年,分析可归因于颗粒物 (PMP) 的缺血性中风的全球疾病负担.
- 通过结合点回归来评估与PMP相关的缺血性中风趋势.
- 通过贝叶斯年龄-周期-队列建模,预测到2050年PMP相关的缺血性中风的未来负担.
主要方法:
- 利用了2021年全球疾病负担研究的数据.
- 雇员加入点回归分析趋势,计算平均年均百分比变化 (AAPC).
- 应用贝叶斯年龄-周期-队列建模用于未来负担预测.
主要成果:
- 在2021年,与PMP相关的缺血性中风导致905,600人死亡,1830万DALY,达到创纪录的高点.
- 死亡人数增加了32.94% (1990-2021年),而年龄标准化死亡率 (ASDR) 减少了46.65% (AAPC: -2.09).
- 环境颗粒物污染 (APMP) 在中等和高SDI地区带来了负担,而家庭空气污染 (HAP) 在低SDI地区持续存在. 男性的死亡率和DALY比女性高.
结论:
- 紧急,有针对性的污染控制战略对于解决APMP和HAP相关的缺血性中风的双重负担至关重要.
- 干预措施必须考虑区域差异,专注于APMP的高收入和中等收入地区,以及HAP的低资源环境.
- 量身定制的方法对于减轻健康差异和实现与空气质量和心血管健康相关的可持续发展目标至关重要.
更多相关视频
09:11Performing Permanent Distal Middle Cerebral with Common Carotid Artery Occlusion in Aged Rats to Study Cortical Ischemia with Sustained Disability
Published on: February 23, 2016
22.1K
10:11Fundus Photography as a Convenient Tool to Study Microvascular Responses to Cardiovascular Disease Risk Factors in Epidemiological Studies
Published on: October 22, 2014
19.3K
相关概念视频
01:30Peripheral Artery Disease I: Introduction
35
Peripheral artery disease (PAD) predominantly results from atherosclerosis, which involves the accumulation of fatty deposits, or plaques, within the walls of arteries. This causes them to narrow and harden, significantly reducing blood flow. PAD predominantly affects the legs, particularly the arteries supplying the thighs and calves. In rare cases, it may involve other arteries, including those in the arms.Etiology of PAD:The principal cause of PAD is atherosclerosis, which results from fatty...
35
01:27Regulation of Stroke Volume
3.5K
The regulation of stroke volume, which is the amount of blood the heart pumps out during each heartbeat, is critical for maintaining a healthy circulatory system. Stroke volume is influenced by three main factors: preload, contractility, and afterload.
Preload refers to the degree of stretch on the heart before it contracts. It's analogous to the stretching of a rubber band; the more it's stretched, the more forcefully it snaps back. This concept is encapsulated in the Frank-Starling law of the...
Preload refers to the degree of stretch on the heart before it contracts. It's analogous to the stretching of a rubber band; the more it's stretched, the more forcefully it snaps back. This concept is encapsulated in the Frank-Starling law of the...
3.5K
01:17Ischemic Heart Disease: Overview
1.4K
Ischemic heart disease occurs when the heart's blood supply dwindles, causing an ominous lack of oxygen and nutrients. This deficiency, stemming from reduced or obstructed blood flow, spells danger, leading to heart muscle damage and dysfunction.
Atherosclerosis, the primary malefactor, orchestrates this dangerous condition. It manifests as the accumulation of fatty deposits, akin to insidious plaques, within arterial walls. As time elapses, these plaques metamorphose, hardening and...
Atherosclerosis, the primary malefactor, orchestrates this dangerous condition. It manifests as the accumulation of fatty deposits, akin to insidious plaques, within arterial walls. As time elapses, these plaques metamorphose, hardening and...
1.4K