慢性病和糖尿病中的嗅觉功能障碍及其与营养因素的关联
Kamyar Iravani1, Aida Doostkam2, Jamshid Roozbeh2
1Department of Otolaryngology, Otolaryngology Research Center, Shiraz University of Medical Sciences, Shiraz, Iran.
Caspian journal of internal medicine
|July 11, 2025
概括
慢性病 (CKD) 和糖尿病 (DM) 患者的嗅觉功能障碍率更高. 这可能与营养因素有关,表明需要早期查和干预.
科学领域:
- 腎臟病學 (nephrology) 是一種醫學專業.
- 内分泌学 在内分泌学.
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
背景情况:
- 嗅觉功能障碍与慢性病 (CKD) 和糖尿病 (DM) 的生活质量降低有关.
- 在CKD和DM中,营养状况的改变与嗅觉功能密切相关.
- 这项研究调查了CKD和DM人群中的嗅觉功能障碍.
研究的目的:
- 评估和比较慢性病和糖尿病患者的嗅觉功能障碍.
- 在这些患者群体中确定与嗅觉障碍相关的潜在风险因素.
主要方法:
- 这是一项涉及77名CKD患者,36名DM患者和27名年龄在20-50岁之间的健康对照者的横截面研究.
- 用伊朗气味识别测试 (Iran-SIT) 来评估嗅觉功能,这是宾夕法尼亚大学气味识别测试 (UPSIT) 的一种版本.
- 统计分析包括P值设置为<0.05和多重回归分析.
主要成果:
- 嗅觉障碍在CKD (54.5%) 和DM (38.9%) 组明显高于对照组 (7.4%) (P=0.001).
- 与DM (18.8±2.1) 和对照组 (20.4±1.2) (P=0.001) 相比,在CKD患者 (16.2±4.2) 中观察到较低的伊朗-SIT得分.
- 在总人口中,男性性别和较低低密度脂蛋白胆固醇 (LDL-C) 与嗅觉功能障碍有关,而在CKD组中,只有LDL-C与嗅觉功能障碍有关.
结论:
- 与健康人相比,患有CKD和DM的患者患有嗅觉功能障碍的患病率更高.
- 与预防性营养因素的潜在联系需要进一步调查.
- 这些发现支持开发查计划和早期干预,用于CKD和DM的嗅觉功能障碍.
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