研究热点和神经病痛微RNA治疗的新兴趋势:一个文献计量分析 (2009-2024)
Yiqiang Zhang1, Shushu Chen2, Jiangtao Chi2
1Discipline of Anesthesiology, Qingdao Medical College, Qingdao University, Qingdao, China.
Frontiers in molecular neuroscience
|July 11, 2025
概括
本文献分析显示,针对神经病痛 (NP) 的微RNA (miRNA) 疗法的研究越来越多. 未来的方向侧重于针对性交付,精度调制和针对这种复杂疾病的个性化策略.
科学领域:
- 生物医学科学 生物医学科学
- 药理学 药理学是指药理学的学科.
- 神经科学是一个神经科学.
背景情况:
- 神经病痛 (NP) 是一种具有有限治疗选择的衰弱性疾病.
- 微RNAs (miRNAs) 已经成为NP的有希望的治疗点.
- 图书统计分析为研究趋势和基于miRNA的NP疗法的未来方向提供了洞察力.
研究的目的:
- 系统地调查不断发展的趋势,研究热点和基于microRNA的治疗神经病痛的未来方向.
- 分析出版模式,作者身份,机构合作和国家贡献.
- 确定该领域的关键研究主题和新兴前沿.
主要方法:
- 从科学网络核心集合 (2009年1月 - 2024年12月) 中对文献进行文献计量分析.
- 分析出版趋势,作者,机构,国家,期刊,共同引用和关键词.
- 识别引文突发和高频率术语.
主要成果:
- 15年来,关于miRNA治疗NP的出版物稳步增加.
- 中国在出版物方面处于领先地位; 美国具有最高的科学影响力.
- 关键的研究热点包括外围神经损伤机制,神经炎症和miRNA差异表达.
结论:
- 微RNA显示了创新的NP治疗的巨大潜力.
- 未来的研究方向包括有针对性的传递系统,感知电路的精确调制和个性化疗法.
- 临床翻译需要解决目标特异性和交付平台生物相容性方面的挑战.
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