经过修改的世卫组织类与患有先天性心脏病的妇女的孕产妇并发症有关
Sara Jonsson1, Bengt Johansson2, Anna-Karin Wikström3
1Department of Public Health and Clinical Medicine, Umea University, 901 87 Umeå, Sweden.
European heart journal open
|July 11, 2025
概括
患有先天性心脏病 (CHD) 的女性怀孕会导致更多的并发症. 经过修改的世卫组织 (mWHO) 分类有助于预测这些怀孕的风险,如剖腹产,早产和子宫前.
科学领域:
- 心脏病学 心脏病学
- 产科 产科 产科 产科 产科
- 生殖医学 生殖医学
背景情况:
- 患有先天性心脏病 (CHD) 的女性怀孕人数正在增加.
- 患有心血管疾病的妇女怀孕与母亲和孩子的风险更高有关.
- 现有的风险分层工具需要在这个不断增长的人群中进行验证.
研究的目的:
- 评估患有心血管疾病的妇女的怀孕和胎儿并发症.
- 评估世界卫生组织 (mWHO) 修改的分类与不良妊娠结果之间的关联.
- 确定mWHO分类对患有心脏病的孕妇风险分层的有用性.
主要方法:
- 利用来自两个国家注册的数据:CHD国家注册和怀孕注册.
- 在2014-2019年期间,确定并匹配了患有心血管疾病 (n=829) 和没有心血管疾病 (n=4137) 的原发性妇女.
- 用修改的世卫组织 (mWHO) 标准对患有心血管疾病的妇女进行分类,并使用后勤回归进行分析.
主要成果:
- 与对照组相比,患有冠状动脉疾病的妇女的剖腹产率 (25.7%对17.2%),早产率 (10.3%对6.4%) 和孕前 (6.2%对4.1%) 较高.
- 高的mWHO类 (III,IV) 与剖腹产 (OR 3.4),早产 (OR 8.3) 和孕前 (OR 3.8) 的几率增加有显著的关联.
结论:
- 怀孕并发症在患有心血管疾病的妇女中更为频繁.
- 世界卫生组织的mWHO分类有效地与患有心脏病的妇女的孕产妇并发症和早产风险相关.
- 世界卫生组织的mWHO分类作为一种有价值的工具,用于CHD怀孕妇女的风险分层,支持当前的临床指南.
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