在Saccharomyces cerevisiae中,Isa2p对于线粒体功能和抗压能力至关重要,因为它允许Rip1p亚单元组装成细胞染色体bc复合体

Luis A Sánchez-Briones1, Mauricio Gomez-Gallardo, Christian Cortes-Rojo

  • 1Laboratorio de Biotecnología Microbiana, Instituto de Investigaciones Químico Biológicas, Universidad Michoacana de San Nicolás de Hidalgo, Morelia, Michoacán, México.

PubMed
概括

铁硫集群生物发生子系统蛋白 Isa2p 对于酵母呼吸功能和氧化应激抵抗是至关重要的. ISA2中的突变破坏了铁硫蛋白的插入,影响了电子运输链超级复合体和乙醇应激耐受性.

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