运动诱导的支气管扩张在健康的男性和女性中没有什么不同
Benjamin P Thompson1, Connor J Doherty2, Paolo B Dominelli1,2
1Faculty of Kinesiology, University of Calgary, Calgary, Alberta, Canada.
Journal of applied physiology (Bethesda, Md. : 1985)
|July 11, 2025
概括
运动诱导的支气管扩张 (EIBD) 在男性和女性之间没有差异. 两性在运动后都显示出气道扩张,肺功能测试的相对变化也相似.
科学领域:
- 身体生理学 身体生理学
- 呼吸系统医学 呼吸系统医学
- 运动科学 运动科学
背景情况:
- 运动诱导的支气管扩张 (EIBD) 是动态运动期间的呼吸道扩张.
- 女性表现出较大的外周血管β2-上腺素活性,但其对气道血管扩张的影响尚不清楚.
- 标准的EIBD评估受胸部气体压缩的影响.
研究的目的:
- 为了研究运动诱导支气管扩张 (EIBD) 的程度,潜在的性别差异.
- 为了比较EIBD使用同时评估压缩和无压缩的流量体积循环.
- 为了确定β2-上腺素活性中的性别差异是否会影响呼吸道对运动的反应.
主要方法:
- 22名健康成年人 (11名女性) 接受了肺功能测试,使用定制体积位移体囊仪.
- 在增量循环运动之前和之后进行最大的呼气机动,直到疲.
- 充血仪允许同时评估压缩和无压缩的流量体积循环.
主要成果:
- 男性的最大氧气吸收比女性更高 (51比42毫升kg-1min-1).
- 在运动后的1秒或中期呼气流中,强迫呼气体积的相对变化没有发现任何显著的性别差异.
- 在两性中都观察到支气管扩张,使用无压缩的流量-体积循环,特别是在中期呼气流中.
结论:
- 运动诱导支气管扩张 (EIBD) 的程度在健康的年轻男性和女性之间是相似的.
- 两性均表现出运动后的气道扩张,肺功能相对变化保持一致.
- 使用体积位移囊仪对胸腔气体压缩的计算证实了EIBD大小中没有性别差异.
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