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Updated: Sep 16, 2025

Co-immunoprecipitation Assay Using Endogenous Nuclear Proteins from Cells Cultured Under Hypoxic Conditions
09:17

Co-immunoprecipitation Assay Using Endogenous Nuclear Proteins from Cells Cultured Under Hypoxic Conditions

Published on: August 2, 2018

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在前列腺癌中,HIF1α-PHD1-FOXA1轴调节缺氧重编程和雄激素信号抑制

Limiao Liang1, Dandan Dong1, Jiaxue Sun1

  • 1MOE Key Laboratory of Metabolism and Molecular Medicine, Department of Biochemistry and Molecular Biology, School of Basic Medical Sciences, Fudan University Shanghai Cancer Center, Shanghai Medical College of Fudan University, Shanghai 200032, China.

Cells
|July 11, 2025
PubMed
概括

前列腺癌的缺氧通过HIF1α-PHD1-FOXA1轴扰乱了基因程序. 这一途径将低氧气与癌症进展联系在一起,并提供了新的治疗点.

关键词:
这就是FOXA1的原因.这就是HIF1α.这是一个PHD1的PHD1版本.系统电池重编程系统的重编程前列腺癌是前列腺癌.

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