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Updated: Sep 16, 2025

Suppression of Pro-fibrotic Signaling Potentiates Factor-mediated Reprogramming of Mouse Embryonic Fibroblasts into Induced Cardiomyocytes
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Yoda1通过BRD4-依赖途径抑制TGFβ诱导的心脏纤维细胞激活

Perwez Alam1,2, Sara M Stiens1, Hunter J Bowles1

  • 1Department of Biomedical Sciences, University of Missouri, Columbia, MO 65211, USA.

Cells
|July 11, 2025
PubMed
概括

这项研究表明,Yoda1通过向BRD4,而不是Piezo1,抑制心脏纤维细胞激活,为心脏纤维化提供了新的治疗策略. 这项研究探讨了纤维化中的离子通道作用.

关键词:
这就是BRD4D.皮洛斯的时间.优达1是什么意思的心脏纤维细胞.纤维细胞激活的激活离子通道 离子通道机器敏感的道.

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