烯在通过嗅觉训练从嗅觉功能障碍中恢复的潜在作用:一篇回顾
Aytug Altundag1,2, Emirhan Harbi3
1Department of Otorhinolaryngology, Biruni University School of Medicine, Istanbul, Turkey. aaltundagkbb@gmail.com.
Molecular biology reports
|July 11, 2025
概括
烯是具有抗炎和神经保护作用的植物化合物,有望改善嗅觉训练. 本综述探讨了它们在增强嗅觉功能恢复方面的潜力.
科学领域:
- 嗅觉神经科学是一种神经科学.
- 药理学 药理学是指药理学的学科.
背景情况:
- 嗅觉功能障碍影响全球许多人,有效治疗方法有限.
- 目前用于嗅觉丧失的临床标准是嗅觉训练.
- 烯是植物衍生化合物,具有已知的抗炎和神经保护性质.
研究的目的:
- 审查在嗅觉训练中的潜在益处.
- 提出一种新的以为中心的嗅觉训练方案.
- 探索烯机制来增强嗅觉功能.
主要方法:
- 对烯特性和对嗅觉通路的影响的文献综述.
- 对烯与细胞信号通路的相互作用进行分析,包括NF-κB和内分泌系统.
- 探索基于烯的嗅觉训练策略.
主要成果:
- 烯通过NF-κB抑制表现出抗炎作用.
- 烯可能调节嗅觉受体并提供神经保护.
- 烯有潜力支持组织再生,增强嗅觉训练有效性.
结论:
- 烯为改善嗅觉训练提供了一个有希望的途径.
- 一个以烯为中心的协议可以增强嗅觉功能障碍的恢复.
- 需要进一步的研究来开发和验证基于的嗅觉疗法.
相关概念视频
Olfaction
The sense of smell is achieved through the activities of the olfactory system. It starts when an airborne odorant enters the nasal cavity and reaches olfactory epithelium (OE). The OE is protected by a thin layer of mucus, which also serves the purpose of dissolving more complex compounds into simpler chemical odorants. The size of the OE and the density of sensory neurons varies among species; in humans, the OE is only about 9-10 cm2.
The olfactory receptors are embedded in the cilia of the...
The olfactory receptors are embedded in the cilia of the...
Olfactory Receptors: Location and Structure
The process of olfaction, also known as the sense of smell, is a sophisticated chemical response system. The specialized sensory neurons that facilitate this process, known as olfactory receptor neurons, are situated in an upper segment of the nasal cavity, known as the olfactory epithelium. Olfactory sensory neurons are bipolar, with their dendrites extending from the epithelium's apex into the mucus that lines the nasal cavity. Airborne molecules, when inhaled, traverse the olfactory...
Physiology of Smell and Olfactory Pathway
Humans detect odors with the help of specialized cells located in the upper part of the nasal cavity, called olfactory receptor neurons (ORNs). ORNs possess hair-like structures called cilia, which are receptive to sensations from the inhaled air. When an odorant molecule binds to a specific receptor on the cell of the cilia, it leads to a series of events that ultimately cause the ORN to send electrical signals to the olfactory bulb in the brain through the olfactory nerves.
The olfactory...
The olfactory...


