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Updated: Sep 16, 2025

Engineering Antiviral Agents via Surface Plasmon Resonance
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默贝科病毒尖蛋白的结构和受体结合活动揭示了人类DPP4适应的关键特征

Hang Yuan1,2, Jingjing Wang1, Yong Ma1

  • 1State Key Laboratory of Respiratory Disease, Guangdong Provincial Key Laboratory of Stem Cell and Regenerative Medicine, Guangdong-Hong Kong Joint Laboratory for Stem Cell and Regenerative Medicine, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, Guangzhou 510530, China.

Science advances
|July 11, 2025
PubMed
概括

来自蝙蝠和松鼠的Merbecoviruses使用尖蛋白来结合人类DPP4. 结构分析揭示了这些动物传染病威胁中保存的结合特征和融合的进化.

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