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Updated: Sep 16, 2025

In Vitro Analysis of E3 Ubiquitin Ligase Function
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赛宾调节K63结合的多基化,以塑造突触内容

Srinivasa R Gandu1,2, Ana R Rodriguez3, Jared Lamp4

  • 1Department of Cell Biology and Neuroscience, Rutgers University, Piscataway, NJ, USA.

Science advances
|July 11, 2025
PubMed
概括

这项研究揭示了由cypin介导的K63-polyubiquitin (K63-polyUb) 修饰如何调节突触功能. 这种蛋白质修饰影响突触的两侧,为神经元信号机制提供了新的见解.

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