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Updated: Sep 16, 2025

Generation of Human Nasal Epithelial Cell Spheroids for Individualized Cystic Fibrosis Transmembrane Conductance Regulator Study
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在上皮细胞中瘤亡因子受体TNFRSF1A的基因型和转录处理:对于囊性纤维化生存的影响

Alexander Uden1, Inga Dunsche2, Sabina Janciauskiene3

  • 1Department for Paediatric Pneumology, Allergology and Neonatology, Hannover Medical School, Hannover, Germany; Biomedical Research in Endstage and Obstructive Lung Disease Hannover (BREATH), German Center for Lung Research (DZL), Germany.

EBioMedicine
|July 11, 2025
PubMed
概括

在TNF受体超级家族1A (TNFR1) 的遗传变异显著影响囊性纤维化患者的存活率. 一种特定的TNFR1转录变异,TNFR1delEx2,可能会调解这种关联,为疾病管理提供新的见解.

关键词:
替代性转录 替代性的转录囊性纤维化症是什么遗传关联研究是研究遗传关联.患者的生存率 患者的生存率这就是TNFRSF1A.瘤亡因子受体受体

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