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Updated: Sep 16, 2025

A Reporter Assay to Analyze Intronic microRNA Maturation in Mammalian Cells
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Published on: June 16, 2022

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FMRP将mRNP目标驱动到翻译性沉默的复合体中

Tatsuaki Kurosaki1, Hana Cho2, Elizabeth T Abshire2

  • 1Department of Biochemistry and Biophysics, School of Medicine and Dentistry, University of Rochester, Rochester, NY 14642, USA; Center for RNA Biology, University of Rochester, Rochester, NY 14642, USA; Department of Biotechnical and Clinical Laboratory Sciences, Jacobs School of Medicine & Biomedical Sciences, State University of New York at Buffalo, Buffalo, NY 14214, USA.

Molecular cell
|July 11, 2025
PubMed
概括

脆弱X综合征 (FXS) 是由于缺乏脆弱X蛋白 (FMRP) 而产生的. 这项研究表明,FMRP主要通过防止40S核糖体亚单元的结合,而不是核糖体停滞来阻止翻译启动.

关键词:
在FMRP中使用FMRP.脆弱的X综合征是什么?这是LC-MS/MS.一个 PABPC1 的人.类似阿素-2的阿素-2类.在 eIF4E 中,您可以使用 eIF4E.胚胎人类皮层神经元mRNP mRNP 在线观看产后小鼠皮质 产后小鼠皮质翻译性的镇压

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