精确的Fick心脏输出估计:直接和同时测量氧气消耗是心力衰竭中必不可少的
Marlus Karsten1, Carlo Vignati2, Beatrice Pezzuto3
1Cardiovascular Health and Exercise Research Group (GEPCardio), Department of Physiotherapy, Graduate Program in Physiotherapy, Santa Catarina State University (UDESC), Florianopolis, Santa Catarina, Brazil; Centro Cardiologico Monzino, IRCCS, Milan, Italy; Department of Clinical Sciences and Community Health, Cardiovascular Section, University of Milan, Milan, Italy.
在血液动力学实验室中直接测量氧气消耗 (VO2) 对于在接受右心导管治疗 (RHC) 的严重心力衰竭患者中准确预测心脏输出 (CO) 至关重要. 病房的测量或估计会损害准确性.
科学领域:
- 心脏病学 心脏病学
- 肺部生理学 肺部生理学
背景情况:
- 预测心脏输出 (CO) 的Fick方法依赖于氧气消耗 (VO2) 的测量.
- 不准确的VO2值可能会在右心导管术 (RHC) 期间损害CO预测的准确性.
研究的目的:
- 为了比较血液动力学实验室 (HL) 中测量的VO2与病房或估计的VO2.
- 用不同的VO2测量来比较严重心力衰竭 (HF) 中的热稀释 (TD) 与衍生的CO值.
主要方法:
- 一项前性观察性研究,涉及80名严重高频率肺炎患者.
- 在HL和病房内,VO2被测量为每次呼吸,或使用公式估计.
- 使用测量/估计的VO2计算CO,并与TD测量进行比较.
主要成果:
- 在HL测量,病房测量和估计的VO2值之间观察到显著差异.
- 来自HL测量的VO2的CO不同于基于病房测量,估计的VO2和TD的CO.
- 在测量和估计的VO2 (r=0.479-0.526) 之间发现了中等的关联;在HL衍生的CO和其他CO值之间发现了更高的关联 (r=0.708-0.765).
结论:
- 在血液动力学实验室中直接测量VO2对于在接受RHC的严重HF患者中准确的CO预测至关重要.
- 病房 VO2 的测量或估计导致 CO 的预测不太准确.
相关概念视频
Cardiac Output I:Effect of Heart Rate on Cardiac Output
Cardiac output (CO) refers to the total amount of blood ejected by one of the ventricles in liters per minute (L/min). In a resting adult, CO ranges from 5 to 6 L/min, adjusting according to the body's metabolic requirements.
Effect of Heart Rate on Cardiac Output
Cardiac output adapts to metabolic demands during stress, physical activity, or illness. The autonomic nervous system regulates heart rate via the sinoatrial node. The parasympathetic nervous system decreases heart...
Cardiac Output and Stroke Volume
In an average resting adult male, the typical cardiac...
Special considerations while measuring oxygen saturation
Ensuring accuracy in vital sign recordings while prioritizing patient comfort and minimizing anxiety is...
Cardiac Output II: Effect of Stroke Volume on Cardiac Output
Preload
Preload refers to the initial elongation of the cardiac myocytes before contraction and is related to the volume of blood filling the heart at the end of diastole, or end-diastolic volume. The...
Exercise and Cardiac Output
Sustained exercise increases the muscles' oxygen demand, which can be...
Assessment of Diffusion and Perfusion
The Role of Diffusion in Respiration
Diffusion is the process by which molecules move from an area of higher concentration to an area of lower concentration. In the respiratory system, this...


