社会经济差异解释了严重喘黑人患者中恶化的增加
Alan P Baptist1, Wenjiong Zhou2, Bradley E Chipps3
1Division of Allergy & Clinical Immunology, Henry Ford Health and Michigan State University, Detroit, Mich.
概括
严重喘 (SA) 的黑人患者的恶化率更高,但当考虑社会经济因素时,这种差异消失了. 解决健康的社会决定因素是减少SA恶化差异的关键.
科学领域:
- 肺病学和过敏症的研究
- 健康差距 研究 研究 研究 研究
- 流行病学 流行病学
背景情况:
- 在美国,患有喘的黑人患者表现出比非黑人患者更高的恶化率.
- 严重喘 (SA) 管理对于患者的治疗结果至关重要.
研究的目的:
- 调查导致严重喘患者中恶化率观察到的种族差异的因素.
- 为了确定社会经济地位,环境,人口统计,吸烟或并发症是否解释了黑人患者中更高的恶化率.
主要方法:
- 观察性CHRONICLE研究美国成年人严重喘 (SA) 不在生物治疗.
- 倾向分数 (PS) 方法用于平衡黑人和非黑人患者组之间的共变量.
- 通用线性模型 (GLM) 评估了PS调整前后的恶化率差异.
主要成果:
- 在分析中,社会经济地位是种族最强的预测因素.
- 在PS调整之前,黑人患者的恶化率高出1.28倍.
- 在PS调整后,黑人种族与恶化率之间的关联不再显著 (率比=0.87).
结论:
- 社会经济因素和健康的社会决定因素可能解释了严重喘的黑人患者中更高的恶化率.
- 解决这些差异可能会减少种族群体之间观察到的恶化风险差异.
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